Francisco Verdeguer Assistant Professor Department of Molecular Mechanisms of Disease, University of Zurich

Francisco Verdeguer's research is focused on the interaction of the metabolism and basic epigenetic regulation in the context of thermogenesis and obesity.

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He studied Biology at the University of Valencia in Spain and did his master thesis with Dr. Vicente Andrés at the Vascular Biology Lab in the Biomedicine Institute of Valencia-CSIC. In 2006, he moved to the Pasteur Institute in Paris, where he studied the role of Hepatocytes Nuclear Factors (HNF1s) and obtained his PhD under the mentorship of Dr. Marco Pontoglio. In early 2011, he started his postdoctoral training at the Dana Farber Cancer Institute/Harvard Medical School with Prof. Pere Puigserver. There, he became interested in the epigenetic and transcriptional regulation of nutrient sensing and energetic metabolism in the context of obesity and type 2 diabetes. In particular, he identified a novel role of the transcription factor Yin Yang 1 in the adaptive thermogenesis. In 2016, Francisco Verdeguer pursued further postdoctoral training in the field of metabolic disorders and inflammation at the Integrated Cardiometabolic Centre with Dr. Myriam Aouadi at the Karolinska Institute before joining the University of Zurich.